BCMTexas Children's HospitalJan and Dan Duncan Neurological Research Institute
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Welcome

Our mission is to understand genetic mechanisms of Alzheimer’s and Parkinson’s disease, and to translate these insights to enhance risk prediction, diagnosis and treatment of these disorders. To achieve these goals, we integrate human genomic analyses with functional investigation in fruit fly models of neurodegenerative disease. Our innovative strategy is revealing genetic pathways of cognition and motor control, and their impact in the aging brain.

Joshua M. Shulman, MD, PhD
Principal Investigator and Assistant Professor
Departments of Neurology, Molecular and Human Genetics, Neuroscience and Program in Developmental Biology
Baylor College of Medicine
Jan and Dan Duncan Neurological Research Institute
Texas Children's Hospital
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News & Events

September 5, 2017
Welcome to Vismaya Kondapali, joining the laboratory as a post-baccalaureate student.

August 24, 2017
Dr. Tom Lee receives an Alzheimer's Association Research Fellowship Award – congratulations!

August 22, 2017
The Shulman Laboratory hosts 5 US Congressional Representatives for the second annual Alzheimer's Research Congressional Update, sponsored by the Alzheimer's Association. See the local news clip and watch the whole event here.

August 1, 2017
Meigen Yu joins the lab as a graduate student from the Baylor College of Medicine Program in Neuroscience. Welcome!

June 27, 2017
Dr. Shamsideen Ojelade receives a Postdoctoral Enrichment Program Fellowship from the Burroughs Wellcome Fund – congratulations!

February 27, 2017
Welcome to Brittany Ripperger, joining the lab as a Research Technician!

February 1, 2017
In a new article, Dr. Shulman and colleagues review how fruit fly experimental models can help solve challenges in understanding many common and genetically complex human disorders. Read the paper.

January 30, 2017
The lab reports on several promising new Parkinson's susceptibility genes based on a cross-species strategy integrating whole-exome sequencing in more than 1,000 subjects with functional followup in Drosophila and other experimental models. Read the paper.

October 20, 2016
In a new article, the lab reports on the discovery of a new Alzheimer's Disease risk gene, TM2D3, and suggests a role in presenilin-mediated processing of APP. Read the paper.

August 25, 2016
Dr. Shamsideen Ojelade, laboratory postdoc, receives an Alzheimer’s Association Research Fellowship Award – congratulations!

July 25, 2016
Katherine Allison joins the lab as a Research Technician – Welcome!

July 24, 2016
Yi-Chen Hsieh, laboratory graduate student, receives a travel award to present her research at the Alzheimer’s Association International Conference – congratulations!

June 25, 2016
In a new article, graduate students Caiwei Guo, Yi-Chen Hsieh, Hui Ye, and Mumine Senturk report surprising new findings from studies of Drosophila models of Alzheimer’s and Parkinson’s disease. Read the paper.

June 6, 2016
Evelyn Hinojosa joins the lab as a Research Technician – Welcome!

February 11, 2016
Amanda Stillwell joins the lab as a Research Technician – Welcome!

January 11, 2016
Dr. Tom Lee joins the lab as a postdoctoral fellow—welcome!

November 23, 2015
In new research published in JAMA Neurology, the lab reports new genetic variants linked to Parkinson's disease risk based on whole exome sequencing in affected families. Read the paper and accompanying editorial.

August 31, 2015
Dr. Shamsideen Ojelade joins the lab as a postdoctoral fellow—welcome!

March 25, 2015
Dr. Laurie Robak, laboratory clinical fellow, receives the Pfizer/ACMG Translational Genomic Scholar Fellowship Award—congratulations!

March 24, 2015
In a new article, Dr. Shulman describes the potential power of integrating human and Drosophila genetic approaches for human disease gene discovery and mechanistic elucidation. Read the paper.

March 16, 2015
Caiwei Guo joins the lab as a graduate student from the Baylor College of Medicine Graduate Program in Neuroscience. Welcome!

March 12, 2015
Dr. Shulman and the NRI make an appearance in "Opportunity Houston" video (0:38), produced by the Greater Houston Partnership. The video is available here: http://www.houston.org/opportunity/

December 22, 2014
Linda Li joins the lab as a research technician. Welcome!

October 13, 2014
Welcome to Jessica Messier and Smriti Agarwal, joining the lab as rotation students from the Baylor College of Medicine Neuroscience and Genetics graduate training programs, respectively.

October 13, 2014
Lizi Kowalis joins the lab as a research technician. Welcome!

September 12, 2014
Dr. Shulman is honored with the Grass Foundation-American Neurological Association (ANA) Award in Neuroscience. He will receive the award at the ANA Annual Meeting (October 12-14, Baltimore, MD).

September 1, 2014
Dr. Shulman is awarded a grant from the National Institutes of Health / National Institute of Neurological Disorders and Stroke. The project, "Functional Validation of Parkinson's Disease Susceptibility Genes in Drosophila," will use fruit flies to define genetic mechanisms underlying disease risk.

August 5, 2014
Welcome to Gabriel Vazquez and Caiwei Guo, joining the lab as rotation students from the Baylor College of Medicine Developmental Biology and Neuroscience graduate training programs, respectively.

July 1, 2014
Dr. Shulman is awarded the New Investigator in Alzheimer's Disease research grant from the American Federation of Aging Research to support studies of synaptic mechanisms underlying susceptibility for Alzheimer's disease.

June 9, 2014
Emily Young joins the lab as a research technician. Welcome!

May 19, 2014
Welcome to Yi-Chen Hsieh and Hui Ye, who join the lab as our first graduate student members from the Baylor College of Medicine Graduate Program in Molecular and Human Genetics.

April 16, 2014
Dr. Shulman joins the faculty of the Department of Neuroscience at Baylor College of Medicine.

Mar 10, 2014
Welcome to Joshua Adams, joining the lab as a rotation student from the Baylor College of Medicine Developmental Biology graduate training program.

Feb 17, 2014
Puja Yogi joins the lab as a research technician. Welcome!

Feb 14, 2014
Dr. Shulman is appointed as a Faculty Associate in the Huffington Center on Aging at Baylor College of Medicine.

Feb 10, 2014
In new research published in JAMA Neurology, the lab discovers links between Parkinson's disease susceptibility genes and motor decline of older persons without Parkinson’s disease. Read the paper.

Jan 30, 2014
Dr. Shulman is awarded a New Investigator Research Grant from the Alzheimer’s Association to study links between aging, genomic instability, and Alzheimer’s disease pathogenesis.

Jan 6, 2014
Welcome to Yi-Chen Hsieh, joining the lab as a rotation student in the Baylor College of Medicine Genetics graduate training program. We also welcome Anita Kaw and Victoria Tobin, who are both joining us as undergraduate students from Rice University.

Oct 1, 2013
Welcome to Janson White, joining the lab as a rotation student in the Baylor College of Medicine Genetics graduate training program.

Sept 25, 2013
In new research published in Human Molecular Genetics, the lab uses fly models to enhance the discovery and functional understanding of genetic risk factors for Alzheimer’s disease. Read the paper.

July 29, 2013
Marissa Ruddy joins the lab as a Baylor College of Medicine rotation student in the Developmental Biology graduate training program--welcome!

July 22, 2013
Welcome to Hecmarie Melendez-Fernandez, joining the lab as a post-baccalaureate student in the BCM SMART Prep program. Learn more about Hecmarie and her research here.

July 8, 2013
Dr. Shulman and colleagues publish new work in JAMA Neurology on genetic risk factors for Alzheimer's disease neuritic plaque pathology. Read the paper, and watch Dr. Shulman discuss the research in this interview from last fall.

June 17, 2013
Welcome to Aditya Srivatsan and Kaveeta Kaw, joining the lab as summer undergraduate students. Aditya and Kaveeta are visiting us from Stanford and the University of Texas at Austin, respectively.

Apr. 1, 2013
The lab welcomes Dr. Laurie Robak and Dr. Nikolaos Giagtzoglou, joining the lab as clinical fellow and research assistant professor, respectively. Learn more about Laurie and Nikos here.


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